Product Description
This pathogen panel offers quantitative analysis of serum Candida antigen and various other parameters, including total IgG, IgA and IgM antibodies specific for Candida.
IgG is the predominant antibody formed from secondary exposure to antigen, and reflects a past or ongoing infection. It is produced as IgM antibody levels decrease after primary exposure. IgG activates complement, and assists the phagocytic system to eliminate antigen from the extravascular space.
IgA is found in mucous secretions and is important in local (mucosal) immunity. Elevated IgA antibodies may reflect a more superficial Candida infection.
IgM is the first antibody formed after primary exposure to antigen, and reflects a present infection. IgM readily activates complement, and assists the phagocytic system to eliminate antigen from the intravascular space.
Pathology Suitability
You should consider taking this pathology test if you suffer from:
- Trauma (infection)
- Surgery
- Underlying disease (diabetes mellitus, Addison’s disease)
- Medications (corticosteroids, antibiotics, oral contraceptives)
- Immunodeficiency
- Pregnancy
- Age (elderly, infancy)
- Malnutrition
